The Global Cell Line Development Market is projected to grow from $4.5 billion to $7.3 billion, at a CAGR of 5.1% in terms of revenue during the forecast period 2021-2030.
The creation of cell lines is a product of life science that is extensively used in numerous essential applications. The process of creating recombinant proteins is aided by the creation of cell lines. Cell line creation provides high-yield cells, which saves time, money, and effort. Most biopharmaceutical companies used cells as an expression host for the synthesis of recombinant monoclonal antibodies.
In the upcoming years, it is anticipated that rising demand for monoclonal antibodies, cancer therapeutics, and the availability of cutting-edge technologies to create novel cell lines will drive market expansion. For the production of products currently in clinical research, the mammalian cell line development division frequently uses human cell lines. As they produce a human protein that has post-translational modifications, human cell lines are commonly used as expression systems (PTMs).
Primary cell lines are cell cultures derived directly from tissues or organs and are often used as models to study specific physiological processes. For example, monoclonal cells are derived from a single cell and exhibit a uniform genetic makeup, making them valuable for studying targeted genetic modifications or drug responses. Comparing monoclonal cell lines to polyclonal cell lines, the former offer more consistency and reproducibility. In cancer research, there is a distinction between cancer cell lines and primary cells, with the former being immortalized cell lines derived from cancerous tissues, while the latter are cells directly isolated from patients' tumors. Books on cell culture and medicine provide comprehensive knowledge of techniques and applications, aiding researchers in the field. Moreover, the field of cell line engineering focuses on developing novel cell lines with desired characteristics through genetic modifications. Professional services are available for cell line development, offering expertise and resources to researchers in need.
Market Dynamics:
Drivers:
The market is expanding as a result of rising demand for biologically derived medicines, the wish for regenerative medicine, and a shift in focus to cutting-edge cancer research. The expansion of top companies' product lines, manufacturers' attention to fast-growing emerging markets like Asia-Pacific, and the inclusion of sizable expenditures to support R&D are some of the elements that contributed to the rise in BPS. In developing countries like India, cell lines have been extensively used as research platforms for drug delivery.
Animal cells have historically been used as the preferred substrate for synthesizing monoclonal antibodies and recombinant proteins because of their propensity for rapid growth, high protein output, and the optimization of the investment system. However, an increase in the use of new technologies offers propel opportunities for cell line development.
Restraints:
The cell line development industry, however, will face obstacles due to high capital costs and high expenditures needed for research and development skills. The creation of stable cell lines is complicated, which will make the market's growth rate even more difficult. The lack of a favorable and insufficient reimbursement situation in developing and underdeveloped economies will also slow the rate of market expansion.
Opportunities:
Due to the demand for cell culture, recombinant cell lines, mammalian cell lines, and associated products, the market for cell line development offers promising growth prospects. The continued use of human diploid cells is anticipated to enable the production of numerous viral vaccines. Launching novel therapies and biosimilars offer an opportunity to make ground in the current industry landscape.
It is anticipated that advancements in culture technologies will have a positive impact on the market expansion for cell line development over the course of the projection period. Furthermore, the use of monoclonal antibodies as therapeutic agents to treat a variety of sick cells presents possibilities for the growth of the cell line development market. These elements will encourage excellent market possibilities.
Key Players:
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American Type Culture Collection
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Lonza Group AG
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Thermo Fisher Scientific Inc.
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GE Healthcare
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Sigma-Aldrich Corporation
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Selexis SA
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Promega Corporation
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Corning Inc.
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WuXiAppTec Inc.
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Sartorius AG
Market Segmentation:
Cell Line Development Market, By Application
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Drug Discovery
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Bioproduction
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Tissue Engineering
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Others
Cell Line Development Market, By Source
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Mammalian Cells
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Non-Mammalian Cells
Cell Line Development Market, By Product
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Equipment
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Media and Reagents
Cell Line Development Market, By Type
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Primary Cell Line
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Hybridoma Cell Line
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Continuous Cell Line
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Recombinant Cell Line
Cell Line Development Market, By Region Type
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North America
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Europe
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Asia-Pacific
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LAMEA
Regional Analysis:
Due to ongoing technological advancements and subsequent new discoveries that have led to the adoption of innovative bioproduction techniques, the North American regional market is expected to account for the largest revenue share by the year 2030. The development is attributed to the existence of rigorous initiatives carried out by study organizations operating in this area, such as Thermo Fisher Scientific Inc., American Type Culture Collection (ATCC), and Sigma-Aldrich Corporation, which offer high-quality biologics services.
Due to rising healthcare spending by the public and private sectors, the Asia Pacific region's market is anticipated to grow fast. It is projected that the biotechnology industry in developing economies would expand significantly during the course of the forecast period. Government programs like public healthcare programs and enhanced healthcare facilities in developing nations are fostering the sector's expansion.
Scope of the report:
Report Coverage |
Details |
Base year |
2021 |
Forecast period |
2030 |
Growth momentum & CAGR |
Accelerate at a CAGR of 5.1% |
YoY growth (%) |
XX% |
Regional analysis |
The Middle East, Europe, North America, Latin America, Asia Pacific, and Africa |
Current Market size |
USD 4.5 Billion |
Forecast market growth |
USD 7.3 Billion |
User
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Introduction
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Market Size Estimation
The overall size of the market has been estimated and validated using both top-down and bottom-up methods. The sizes of other market subsegments have also been thoroughly estimated using these methodologies.
In the top-down technique, the market is divided into segments based on the percentage share of each segment. This method assisted in determining the size of each segment's market. The market size of each segment and its sub-segments was then divided into regional market sizes. This Approach helps mainly with the new Product Launch. It uses Multi-variate Regression Model coupled with Vendor based primary research inputs to forecast to the Market Size.
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